As I shared in this blog post, there is an important link between leaky gut and recurrent miscarriage, likely due to inflammatory and immune reactions to the endometrium.
New research from Italy and Iran has highlighted links between zonulin (a biomarker of intestinal permeability, or “leaky gut”), and inflammation-related pregnancy complications. There were significant increases in serum zonulin in women with gestational diabetes (GDM) compared to healthy controls, and higher zonulin concentration in hypertensive disorders of pregnancy (HDP).
As mentioned in the earlier blog post, leaky gut can be assessed with the intestinal permeability test, and also by serum (blood) levels of zonulin for those that would prefer to not undergo the sugar test. Leaky gut is treatable and well worth addressing during pre-conception.
I hope you have found this helpful, and do let me know if you have any questions!
If you are hungry for more evidence-based information for your fertility or pregnancy journey, visit www.myhealthypregnancyplan.com for free webinars and complete programs.
And if you are a care-provider looking for evidence-based resources for your fertility or pregnancy patients, please get in touch with us at support@myhealthypregnancyplan.com, or visit www.myhealthypregnancyplan.com/ce-courses-for-naturopathic-doctors.
In health,
Dr Jocelyn Land-Murphy, ND
Terra Life
Disclaimer: The information and content provided is for general educational and informational purposes only and is not professional medical advice, nor is it intended to be a substitute therefore. Please consult the Disclaimer and Terms of Use for full details.
References:
Daneshvar, M. et al. (2022). Zonulin levels in complicated pregnancy: a systematic review and meta-analysis. Journal of Obstetrics and Gynaecology.