The role a healthy microbiome plays in fertility and pregnancy maintenance is a favourite subject of mine, as seen in many prior blog posts and my online pregnancy course.
New research from Ukraine’s Bukovinian State Medical University has taken a deeper look specifically at endometriosis-related infertility. A key mechanism in endometriosis development is inflammation, which triggers disease progression that results in progressive tissue damage, chronic disease and fertility challenges. Now, this newest study looks at the role probiotics can play in decreasing inflammation and infertility rates in this population.
The study compared endometriosis-affected women who were instructed to supplement with 10B Lactobacillus twice daily for the month before IVF, compared to non-probiotic-supplemented IVF patients. Researchers measured levels of NLRP3 inflammasome before and after the treatment phase – and found a “substantial reduction” with probiotic treatment.
Their conclusion: “Incorporating probiotics as part of a comprehensive preparation regimen before assisted reproductive technologies leads to a notable enhancement in patient well-being and a substantial reduction in mRNA expression of the NLRP3 inflammasome.”
This is even more great news for both endometriosis treatment and fertility supports!
I hope you have found this helpful, and do let me know if you have any questions!
If you are hungry for more evidence-based information for your fertility or pregnancy journey, visit www.myhealthypregnancyplan.com for free webinars and complete programs.
And if you are a care-provider looking for evidence-based resources for your fertility or pregnancy patients, please get in touch with us at support@myhealthypregnancyplan.com, or visit www.myhealthypregnancyplan.com/ce-courses-for-naturopathic-doctors.
In health,
Dr Jocelyn Land-Murphy, ND
Terra Life
Disclaimer: The information and content provided is for general educational and informational purposes only and is not professional medical advice, nor is it intended to be a substitute therefore. Please consult the Disclaimer and Terms of Use for full details.
References:
Bakun, O. et al. (2023). Probiotics and NLRP3 mRNA inflammasome levels in women with endometriosis-related infertility undergoing assisted reproductive technologies. Journal of Medicine and Life